Lionel Barrymore

Dr. Josiah Glass

Jean Arthur

Maria Theresa 'Terry' O'Reilly

Chester Morris

Jeff Crane

Joseph Calleia

Sonny 'Dinkie' Black

Paul Kelly

Special Agent James Duff

Lewis Stone

Prison Warden

Paul Hurst

Rufe Parker

George E. Stone

Butch

Sam Baker

Mose Jones

William Bailey

Federal Agent (uncredited)

Brooks Benedict

Bar Patron (uncredited)

Ed Brady

Convict in Prison (uncredited)

Lane Chandler

Train Conductor (uncredited)

Cora Sue Collins

Little Girl (uncredited)

Helene Costello

Convict Wife (uncredited)

J. Walter Ruben