Kiefer Sutherland

William S. Burroughs

Courtney Love

Joan Vollmer Burroughs

Ron Livingston

Allen Ginsberg

Norman Reedus

Lucien Carr

Sam Trammell

Lee

Alec Von Bargen

Heard

Tommy Perna

Dwight

Daniel Martínez

Jack Kerouac

Kyle Secor

Dave Kammerer

Luisa Huertas

Maria (uncredited)

Lisa Sheridan

Sadie

Gary Walkow