Basil Rathbone

Sherlock Holmes

Nigel Bruce

Dr. John Watson

Aubrey Mather

Alastair

Paul Cavanagh

Simon Merrivale

Dennis Hoey

Inspector Lestrade

Harry Cording

John Simpson

Holmes Herbert

Alan Cosgrave

Sally Shepherd

Mrs. Monteith

Gavin Muir

Chalmers

Florette Hillier

Alison MacGregor

David Clyde

Alex MacGregor

Doris Lloyd

Bessie

Cyril Delevanti

Stanley Raeburn (uncredited)

Alec Craig

Angus (uncredited)

Richard Alexander

Ralph King (uncredited)

Roy William Neill