Boris Karloff

Dr. Fu Manchu

Lewis Stone

Nyland Smith

Karen Morley

Sheila Barton

Charles Starrett

Terence Granville

Myrna Loy

Fah Lo See

Jean Hersholt

Von Berg

Lawrence Grant

Sir Lionel Barton

David Torrence

McLeod

C. Montague Shaw

Curator Dr. Fairgyle - British Museum Official (uncredited)

Steve Clemente

Knife Thrower (uncredited)

Allen Jung

Coolie (uncredited)

Chris-Pin Martin

Potentate (uncredited)

Edward Peil Sr.

Coolie Spy (uncredited)

Willie Fung

Ship's Steward (uncredited)

E. Alyn Warren

Goy Lo Sung - Fu Manchu Messenger (uncredited)

Charles Brabin