George Clinton

Host

Robert Guillaume

Gleason Golightly (segment 'Space Traders')

Michele Lamar Richards

Gail Golightly (segment 'Space Traders')

Jason Bernard

Bernard Shields (segment 'Space Traders')

Edward Edwards

Chief of Staff (segment 'Space Traders')

George Wallace

Piggy (segment 'Space Traders')

Brian Reddy

Vice President (segment 'Space Traders')

Larry Anderson

Stryker O'Rourke (segment 'Space Traders')

Brock Peters

Minister Coombs (segment 'Space Traders')

Bob Gunton

President Ellis (segment 'Space Traders')

Nicholas Turturro

Father Carlos (segment 'The First Commandment')

Efrain Figueroa

Padrino (segment 'The First Commandment')

Richard Herd

Cardinal (segment 'The First Commandment')

Paula Jai Parker

Tang (segment 'Tang')

Chi McBride

T-Bone (segment 'Tang')

Reginald Hudlin

Warrington Hudlin

Kevin Rodney Sullivan