Neil Patrick Harris

Dr. Philip O'Hanlon (voice)

Bea Miller

Virginia O'Hanlon (voice)

Jennifer Love Hewitt

Mrs. Laura O'Hanlon (voice)

Alfred Molina

Francis Church (voice)

Robb Pruitt

Santa (voice)

Andrew Cherry

George (voice)

Taylor Hay

Taylor (voice)

Michael Buscemi

Scraggly Santa (voice)

Pete Circuitt