Michael C. Hall

Jack

Sarah Silverman

Cheri

Rainn Wilson

Joel

Ben Schwartz

Nathan

Kate Mara

Meg

Taraji P. Henson

Mary

Judy Greer

Laura

Alicia Witt

Amy

Ron Rifkin

Henry Meyerwitz

Lesley Ann Warren

Marilyn

Octavia Spencer

Alison

Rich Delia

Waiter

Stephen Tobolowsky

Ephraim

Lewis Black

Narrator (voice)

Kulap Vilaysack

Lily

Barry W. Blaustein