Gian Maria Volonté

Charles 'Lucky' Luciano

Edmond O'Brien

Commissioner Harry J. Anslinger

Rod Steiger

Gene Giannini

Vincent Gardenia

Colonel Charles Poletti

Silverio Blasi

Italian Captain

Charles Cioffi

Vito Genovese

Larry Gates

Judge Herlands

Magda Konopka

Contessa

Jacques Monod

French Commissioner

Karin Petersen

Igea Lissoni

Dino Curcio

Don Ciccio

Charles Siragusa

Himself

Aldo De Martino

(uncredited)

Frank Adonis

Killer of Gene Giannini in New York (uncredited)

Francesco Rosi